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Alprazolam Xr

Generic: Alprazolam

Rx only
Benzodiazepine✓ FDA-verified
View full FDA label ↗
Alprazolam XR is a medication used to treat panic disorder, which can occur with or without fear of open spaces. It works by enhancing the effects of a natural calming substance in the brain, helping to reduce anxiety and panic symptoms. You take it as a tablet once a day, preferably in the morning, starting with a dose of 0.5 mg to 1 mg, and it can be increased to a maximum of 6 mg daily based on your response. It's important to know that this medication should not be taken if you have a known allergy to alprazolam or other similar drugs. Additionally, if you're taking strong medications that affect liver enzymes, like ketoconazole, you should avoid using alprazolam XR, as it can increase the risk of side effects.

Uses

  • Panic disorder.
  • Agoraphobia.

Dosage

Start with 0.5 mg to 1 mg once daily, preferably in the morning.
Dosage may be increased by 1 mg every 3 to 4 days.
Total daily dosage is usually between 3 mg to 6 mg.
Swallow tablets whole; do not divide, crush, or chew.
Always follow your doctor's specific instructions for your dose.

Side effects

Common

sedationsomnolencememory impairmentcoordination problemsconstipationnausearisk of respiratory depression

Serious

dependencewithdrawal reactionsand overdose
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Warnings

⚠ Important warnings

  • Risk of severe sedation and respiratory issues when used with opioids.
  • Potential for abuse, misuse, and addiction.
  • Withdrawal symptoms can be life-threatening if stopped suddenly.
  • Use with caution in elderly patients and those with liver issues.

Drug interactions

  • Opioidsincreased risk of respiratory depressionMonitor
  • CNS depressantsadditive effects can cause sedationCaution
  • Digoxinincreased risk of digoxin toxicityMonitor
  • Strong CYP3A inhibitorsincreased risk of adverse reactionsMonitor
  • CYP3A inducersmay reduce effectiveness of alprazolam.Caution

Ask about this drug

Answers pulled from the FDA label only.

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).