MedDataToolChlorpromazine is a medication used to treat conditions like schizophrenia, severe behavioral problems in children, and to help control nausea and vomiting. It works by affecting certain chemicals in the brain to help improve mood and reduce anxiety. Adults typically start with a dose of 25 mg to 50 mg taken by injection or orally, and the maximum daily dose can go up to 800 mg depending on individual needs. It's important to know that this medication is not approved for elderly patients with dementia-related psychosis, as it may increase the risk of death in that population. Additionally, avoid using alcohol while taking this medication, as it can enhance side effects and lead to low blood pressure.
✦
Uses
- Schizophrenia.
- Nausea and vomiting.
- Restlessness and apprehension before surgery.
- Acute intermittent porphyria.
- Adjunct treatment for tetanus.
- Manic episodes in manic-depressive illness.
- Intractable hiccups.
- Severe behavioral problems in children (1 to 12 years).
◷
Dosage
Adults: Adjust based on individual needs and symptoms.
Elderly: Lower doses are usually sufficient; monitor closely.
Pediatric: 1/4 mg/lb body weight for severe behavioral problems.
For nausea: 25 mg IM every 3-4 hours as needed.
For surgery: 12.5 to 25 mg IM 1-2 hours before operation.
Always follow your doctor's specific instructions for your dose.
⚠
Side effects
Common
Drowsinessespecially in the first weeksJaundice resembling infectious hepatitisSore throat or signs of infectionHypotensiondizzinessand faintingNeuromuscular reactions like muscle spasmsTardive dyskinesia with involuntary movements
🛑
Warnings
⚠ Important warnings
- Increased risk of death in elderly with dementia-related psychosis.
- Avoid use in children with Reye's syndrome.
- Monitor for allergic reactions to sulfites.
- Tardive dyskinesia may develop with long-term use.
- Neuroleptic Malignant Syndrome (NMS) can be fatal.
- Caution in patients with liver disease.
⇄
Drug interactions
- Alcoholmay increase drowsiness and hypotensionCaution
- Guanethidinemay reduce its blood pressure effect.Caution
Ask about this drug
Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).