MedDataToolCholestyramine is a medication used to help lower high cholesterol levels and relieve itching caused by certain liver problems. It works by binding to bile acids in the intestines, which helps reduce cholesterol levels in the blood. You typically take it as a powder mixed with water or another beverage, starting with one scoopful (about 9 grams) once or twice a day, and the maximum dose is six scoopfuls daily. It's important to know that this medication should not be taken by anyone with complete biliary obstruction, where bile cannot flow into the intestine. Additionally, it may work better when combined with certain cholesterol-lowering medications like statins.
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Uses
- High cholesterol (primary hypercholesterolemia).
- Pruritus from partial biliary obstruction.
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Dosage
Start with 1 scoopful once or twice a day.
Maintenance is 2 to 4 scoopfuls daily, divided into two doses.
Take with meals to avoid affecting other medications.
Mix powder with water or fluid before taking.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
constipationabdominal discomfortflatulenceintestinal obstruction
Serious
vitamin deficienciesliver function abnormalities
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Warnings
⚠ Important warnings
- Contains phenylalanine; caution for phenylketonurics.
- Monitor for constipation, especially in older adults.
- Exclude secondary causes of high cholesterol before use.
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Drug interactions
- Pravastatinmay enhance cholesterol-lowering effectsCaution
- Lovastatinmay enhance cholesterol-lowering effectsCaution
- Simvastatinmay enhance cholesterol-lowering effectsCaution
- Fluvastatinmay enhance cholesterol-lowering effects.Caution
Ask about this drug
Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).