MedDataToolCitalopram is a medication used to treat major depressive disorder in adults by helping to increase the levels of serotonin, a chemical in the brain that affects mood. It comes in tablet form and is typically taken once daily, starting at a dose of 20 mg, which can be increased to a maximum of 40 mg after one week. It's important to know that citalopram should not be taken with monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping them, as this can lead to serious side effects. Additionally, older adults, those with liver problems, and certain genetic factors may require a lower maximum dose of 20 mg.
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Uses
- major depressive disorder (MDD).
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Dosage
Start with 20 mg once daily.
After one week, may increase to 40 mg once daily.
Take once daily, with or without food.
Maximum dose for those over 60 or with liver issues is 20 mg.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
nauseadry mouthdizzinessinsomniafatigue
Serious
suicidal thoughtsserotonin syndromeseizuresincreased bleeding risk
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Warnings
⚠ Important warnings
- Increased risk of suicidal thoughts in young adults.
- Not approved for pediatric patients.
- Monitor for worsening depression or suicidal thoughts.
- Avoid use with MAOIs to prevent serotonin syndrome.
- Caution in patients over 60 or with liver impairment.
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Drug interactions
- MAOIsrisk of serotonin syndromeCaution
- Pimozideincreased risk of heart issuesMonitor
- CYP2C19 inhibitorsincreased risk of heart issuesMonitor
- Antiplatelet agentsincreased risk of bleedingMonitor
- Other serotonergic drugsrisk of serotonin syndrome.Caution
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Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).