MedDataToolCleocin Phosphate is a medication used to treat serious infections caused by certain bacteria, including those that can affect the lungs, skin, and reproductive system. It works by stopping bacteria from making proteins they need to grow, which helps to eliminate the infection. The medication is given either through an injection into a muscle or through an intravenous (IV) line, with adults typically starting at a dose of 600 to 1200 mg per day, which can be increased to a maximum of 4800 mg for severe cases. It's important to know that this medication can cause a serious type of diarrhea called Clostridioides difficile-associated diarrhea, so if you experience diarrhea while taking it, you should contact your doctor immediately. Additionally, if you have a history of allergic reactions to clindamycin or lincomycin, you should not use this medication.
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Uses
- Lower respiratory tract infections (like pneumonia).
- Skin and skin structure infections.
- Gynecological infections (like endometritis).
- Intra-abdominal infections (like peritonitis).
- Septicemia.
- Bone and joint infections.
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Dosage
Adults: 600–1200 mg daily in 2-4 doses.
Severe infections: 1200–2700 mg daily in 2-4 doses.
Pediatric patients (1 month to 16 years): 20-40 mg/kg/day in 3-4 doses.
Pediatric patients (less than 1 month): 15-20 mg/kg/day in 3-4 doses.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
Abdominal painnauseavomitingunpleasant taste
Serious
Clostridioides difficile colitissevere skin reactionsanaphylaxis
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Warnings
⚠ Important warnings
- Risk of Clostridioides difficile-associated diarrhea (CDAD).
- Anaphylactic and severe hypersensitivity reactions.
- Benzyl alcohol toxicity in neonates.
- Potential nephrotoxicity, monitor renal function.
- Not for treating meningitis.
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Drug interactions
- Neuromuscular blockersmay enhance effectsCaution
- CYP3A4 inhibitorsmay increase clindamycin levelsCaution
- CYP3A4 inducersmay reduce clindamycin effectivenessCaution
Ask about this drug
Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).