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Contepo

Generic: Fosfomycin Disodium

Rx only
Antibacterial✓ FDA-verified
View full FDA label ↗
Contepo is an antibacterial medication used to treat complicated urinary tract infections in adults, including kidney infections caused by certain bacteria. It works by disrupting the bacteria's ability to build their protective walls, ultimately killing them. The medication is given through an intravenous (IV) infusion, typically starting at a dose of 6 grams every 8 hours for up to 14 days, depending on kidney function. It's important to know that Contepo should not be used if you have a serious allergy to fosfomycin or any of its ingredients. Additionally, if you are undergoing hemodialysis, the timing of when you take Contepo may need to be adjusted, as a significant amount of the drug is removed during the procedure.
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Uses

  • Complicated urinary tract infections (cUTI).
  • Acute pyelonephritis.
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Dosage

6 grams every 8 hours by IV infusion for up to 14 days for adults with normal kidney function.
Doses may vary based on kidney function.
Administer after hemodialysis on hemodialysis days.
Always follow your doctor's specific instructions for your dose.
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Side effects

Common

NauseaVomitingDiarrheaHeadacheLow potassium levelsLow calcium levelsLow phosphate levelsNeutropenia

Serious

Increased liver enzymesSerious allergic reactionsClostridioides difficile-associated diarrhea
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Warnings

⚠ Important warnings

  • Use only for infections caused by susceptible bacteria to prevent drug resistance.
  • Monitor kidney function and adjust dosage as needed.
  • Risk of QT prolongation affecting heart rhythm.
  • Not recommended for patients with severe kidney impairment without adjustment.
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Drug interactions

  • Drugs that prolong QT intervalincreased risk for heart rhythm issuesMonitor

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Answers pulled from the FDA label only.

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).