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Diltiazem

Generic: Diltiazem Hydrochloride

Rx only
Calcium channel blocker✓ FDA-verified
View full FDA label ↗
Diltiazem is a medication used to treat high blood pressure and chest pain from angina. It works by relaxing the blood vessels, which helps lower blood pressure and makes it easier for the heart to get enough oxygen. You usually take it in the form of extended-release capsules, starting with a dose of 180 to 240 mg once daily, and it can go up to a maximum of 480 mg once daily if needed. It's important to know that diltiazem can cause slow heart rates, especially in people with certain heart conditions. Additionally, if you're taking beta-blockers, you should be cautious, as using them together can affect how your heart functions.

Uses

  • Hypertension.
  • Chronic stable angina.
  • Angina due to coronary artery spasm.

Dosage

Start with 180 to 240 mg once daily for hypertension.
For angina, start with 120 or 180 mg once daily.
Doses may be adjusted based on individual needs.
Maximum effect for hypertension usually seen after 14 days.
Always follow your doctor's specific instructions for your dose.

Side effects

Common

Dizzinessconstipationdry mouthand fatigue

Serious

Congestive heart failuresevere allergic reactionsand heart block
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Warnings

⚠ Important warnings

  • May cause slow heart rates or heart block.
  • Caution in patients with heart failure or conduction issues.
  • Monitor blood pressure for possible hypotension.
  • Use with beta-blockers or digitalis may increase heart risks.
  • Avoid alcohol as it may increase side effects.

Drug interactions

  • Beta-blockersmay increase heart conduction issuesCaution
  • Digoxinmay increase digoxin levelsCaution
  • Midazolammay increase sedation effectsCaution
  • Carbamazepinemay increase carbamazepine levelsCaution
  • Cimetidinemay increase diltiazem levels.Caution

Ask about this drug

Answers pulled from the FDA label only.

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).