MedDataToolDulaglutide, also known as Trulicity, is a medication used to help manage blood sugar levels in adults and children aged 10 and older with type 2 diabetes. It works by helping your body release more insulin when you need it and reducing the amount of sugar your liver makes. You take it as an injection under the skin once a week, starting at a dose of 0.75 mg, which can be increased to a maximum of 4.5 mg if more control is needed. It's important to know that this medication should not be used if you have a personal or family history of certain thyroid tumors. Additionally, if you're taking insulin or other medications that increase insulin, there may be a risk of low blood sugar, so be sure to discuss this with your healthcare provider.
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Uses
- Type 2 diabetes mellitus in adults and pediatric patients 10 years and older.
- Reduce risk of major cardiovascular events in adults with type 2 diabetes and cardiovascular disease or risk factors.
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Dosage
Adults: Start with 0.75 mg once weekly, can increase to 1.5 mg after 4 weeks.
Maximum dose is 4.5 mg once weekly.
Pediatric: Start with 0.75 mg once weekly, can increase to 1.5 mg after 4 weeks.
Administer at any time of day with or without food.
Inject in the abdomen, thigh, or upper arm.
Rotate injection sites.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
Nauseadiarrheavomitingabdominal paindecreased appetiteRisk of thyroid tumors
Serious
pancreatitissevere gastrointestinal diseaseacute kidney injury
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Warnings
⚠ Important warnings
- Risk of thyroid C-cell tumors; contraindicated in patients with a history of medullary thyroid carcinoma.
- Not for type 1 diabetes mellitus.
- Not recommended for patients with severe gastrointestinal disease.
- Consider other diabetes treatments for patients with a history of pancreatitis.
- Monitor for hypoglycemia when used with insulin or insulin secretagogues.
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Drug interactions
- Oral medicationsmay reduce absorption due to delayed gastric emptyingCaution
- Insulin secretagoguesincreased risk of hypoglycemia.Monitor
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Answers pulled from the FDA label only.
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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).