Endometrin is a medication that contains progesterone and is used to help support embryo implantation and early pregnancy for women undergoing assisted reproductive technology (ART) treatments. It works by preparing the lining of the uterus to receive and maintain a pregnancy. You take it as a vaginal insert, starting with a dose of 100 mg two or three times a day, beginning the day after an egg retrieval and continuing for up to 10 weeks. It's important to know that Endometrin should not be used if you have a history of allergic reactions to progesterone or if you have undiagnosed vaginal bleeding. Additionally, if you are taking blood thinners, such as warfarin, you should discuss this with your healthcare provider, as it may interact with the medication.
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Uses
- Support embryo implantation.
- Support early pregnancy.
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Dosage
100 mg administered vaginally two or three times daily.
Start the day after oocyte retrieval.
Continue for up to 10 weeks.
Efficacy in women 35 and older not clearly established.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
Post-oocyte retrieval painAbdominal painNauseaOvarian hyperstimulation syndromeFatigueHeadache
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Warnings
⚠ Important warnings
- Efficacy in women 35 years and older not established.
- Not recommended with other vaginal products.
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Drug interactions
- Rifampinmay increase progesterone eliminationCaution
- Carbamazepinemay increase progesterone eliminationCaution
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Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
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