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Exforge Hct

Generic: Amlodipine Valsartan And Hydrochlorothiazide

Rx only
Thiazides✓ FDA-verified
View full FDA label ↗
Exforge HCT is a medication used to treat high blood pressure, helping to lower the risk of serious heart problems like strokes and heart attacks. It combines three ingredients that work together: one relaxes blood vessels, another blocks certain hormones that can raise blood pressure, and the third helps the body get rid of extra salt and water. You take it as a tablet once a day, starting with a dose that can be increased to a maximum of 10/320/25 mg after two weeks if needed. It's important to know that this medication should not be used in patients who are unable to produce urine or are allergic to sulfonamide drugs. Additionally, if you have diabetes, you should avoid taking Exforge HCT with aliskiren, a medication used to treat high blood pressure.
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Uses

  • Hypertension.
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Dosage

Take once daily.
The dose may be increased after 2 weeks.
Maximum dose is 10/320/25 mg.
Can be used as add-on therapy for patients not controlled on two antihypertensive classes.
May be substituted for its individually titrated components.
Always follow your doctor's specific instructions for your dose.
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Side effects

Common

Common side effects include dizzinessheadacheand fatigueOther common effects are peripheral edemamuscle spasmsand nausea

Serious

Serious side effects may include hypotension and angioedema
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Warnings

⚠ Important warnings

  • Discontinue if pregnancy is detected due to fetal toxicity risk.
  • Not for initial treatment of hypertension.
  • Monitor for hypotension and edema when combined with CYP3A inhibitors.
  • Avoid dual blockade of the renin-angiotensin system.
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Drug interactions

  • Sildenafilmay cause low blood pressureCaution
  • Simvastatinincreases exposure to simvastatinMonitor
  • Cyclosporinemay increase risk of hyperuricemiaCaution
  • Lithiumincreased risk of lithium toxicityMonitor
  • NSAIDsmay lead to renal impairment.Caution

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Answers pulled from the FDA label only.

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).