MedDataToolFarxiga is a medication used to help reduce the risk of serious kidney problems, heart failure, and cardiovascular issues in adults with chronic kidney disease, heart failure, or type 2 diabetes. It works by preventing the reabsorption of sugar in the kidneys, which helps lower blood sugar levels and can also reduce strain on the heart. You typically take it as a pill, starting with a dose of 10 mg once daily, which can be increased to a maximum of 10 mg daily for certain conditions. It's important to know that Farxiga is not recommended for people with a history of severe allergic reactions to it. Additionally, if you're taking insulin or certain other diabetes medications, you may need to be cautious as this can increase the risk of low blood sugar.
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Uses
- Chronic kidney disease at risk of progression.
- Heart failure.
- Type 2 diabetes with cardiovascular disease.
- Type 2 diabetes to improve glycemic control.
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Dosage
5 mg once daily for glycemic control if eGFR 45 or greater. 10 mg once daily for other indications if eGFR 45 or greater. 10 mg once daily if eGFR 25 to less than 45.
Not recommended for initiation if eGFR less than 25.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
Female genital mycotic infectionsNasopharyngitisUrinary tract infectionsBack painIncreased urinationDiabetic ketoacidosisVolume depletionUrosepsis and pyelonephritisHypoglycemia with insulin useNecrotizing fasciitis of the perineum
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Warnings
⚠ Important warnings
- Not for type 1 diabetes.
- Not for type 2 diabetes with eGFR less than 45.
- Not for chronic kidney disease with polycystic kidney disease.
- Monitor renal function before starting.
- Risk of dehydration and low blood pressure.
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Drug interactions
- Insulinincreased risk of hypoglycemiaMonitor
- Insulin secretagoguesincreased risk of hypoglycemiaMonitor
- Lithiummay decrease serum lithium concentrationsCaution
- Urine glucose testsmay show false positives. 1,5-AG assay — unreliable for monitoring glycemic controlMonitor
Ask about this drug
Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).