MedDataToolFentanyl transdermal system is a patch used to manage severe and ongoing pain in patients who are already tolerant to opioids. It works by interacting with specific receptors in the brain to reduce the feeling of pain. The patch is applied to the skin and can be worn continuously for up to 72 hours, with a starting dose of 25 micrograms per hour, which can be increased based on individual needs, but should not exceed 300 micrograms per hour. It is important to note that this medication is not suitable for patients who are not already using opioids, as it can cause serious breathing problems. Additionally, using fentanyl with certain medications that affect the liver, like ritonavir, can increase the risk of dangerous side effects, so it’s crucial to inform your doctor about all medications you are taking.
✦
Uses
- Severe and persistent pain in opioid-tolerant patients.
◷
Dosage
Prescribed only by knowledgeable healthcare providers.
Use the lowest effective dose for the shortest time.
Each patch is worn for up to 72 hours.
In patients with mild to moderate liver or kidney issues, start with half the usual dose.
Always follow your doctor's specific instructions for your dose.
⚠
Side effects
Common
nauseavomitingdizzinessinsomniaconstipationfatiguerespiratory depression
Serious
addictionoverdoseaccidental exposure
🛑
Warnings
⚠ Important warnings
- Risk of addiction, abuse, and misuse.
- May cause life-threatening respiratory depression.
- Accidental exposure can be fatal, especially in children.
- Avoid use with benzodiazepines or other CNS depressants.
- Not for use in opioid-non-tolerant patients.
⇄
Drug interactions
- Benzodiazepinesincreased risk of sedation and respiratory depressionMonitor
- CYP3A4 inhibitorsmay increase fentanyl levels and risk of overdoseCaution
- CYP3A4 inducersmay decrease fentanyl effectivenessCaution
- Serotonergic drugsrisk of serotonin syndromeCaution
- Mixed agonist/antagonist opioidsmay reduce fentanyl effectiveness.Caution
Ask about this drug
Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).