MedDataToolFluconazole is a medication used to treat various fungal infections, including vaginal yeast infections, oral and esophageal candidiasis, and cryptococcal meningitis. It works by stopping the growth of fungi in the body. You can take it as a tablet, usually starting with a single dose of 150 mg for vaginal infections or 200 mg on the first day for other infections, with a maximum daily dose that can go up to 400 mg depending on the condition. It's important to be cautious if you have liver problems, as fluconazole can cause liver injury in some cases. Additionally, if you're taking medications that can affect heart rhythm, like erythromycin or quinidine, you should avoid using fluconazole together with them.
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Uses
- Vaginal candidiasis.
- Oropharyngeal candidiasis.
- Esophageal candidiasis.
- Systemic Candida infections.
- Cryptococcal meningitis.
- Candidiasis prophylaxis in bone marrow transplant patients.
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Dosage
150 mg as a single dose for vaginal candidiasis. 200 mg on the first day, then 100 mg daily for oropharyngeal candidiasis. 200 mg on the first day, then 100 mg daily for esophageal candidiasis.
Doses up to 400 mg daily for systemic Candida infections. 400 mg on the first day, then 200 mg daily for cryptococcal meningitis. 400 mg once daily for candidiasis prevention in bone marrow transplant patients.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
headachenauseaabdominal paindiarrheadizziness
Serious
liver injuryanaphylaxisskin rashseizures
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Warnings
⚠ Important warnings
- Caution in patients with liver dysfunction.
- Risk of serious hepatic toxicity.
- Monitor for liver function abnormalities.
- Anaphylaxis has been reported.
- Discontinue if severe skin reactions occur.
- Potential fetal harm if used during pregnancy.
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Drug interactions
- Warfarinincreases prothrombin timeMonitor
- Phenytoinincreases phenytoin levelsMonitor
- Cyclosporineincreases cyclosporine levelsMonitor
- Midazolamincreases midazolam levelsMonitor
- Rifampindecreases fluconazole levelsCaution
- Quinidinemay cause QT prolongationCaution
Ask about this drug
Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).