MedDataToolFluphenazine Decanoate is a long-acting medication used to help manage symptoms in patients with chronic schizophrenia. It works by affecting certain chemicals in the brain to help improve mood and behavior. The medication is given as an injection, usually starting at a dose of 12.5 to 25 mg, and can be given every three weeks, with a maximum dose of 100 mg. It's important to know that this medication is not approved for treating elderly patients with dementia-related psychosis, as it can increase the risk of death in that group. Additionally, be cautious if you are taking other medications that can depress the central nervous system, like alcohol or certain pain relievers, as they may increase the effects of fluphenazine.
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Uses
- chronic schizophrenia.
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Dosage
Initial dose: 12.5 to 25 mg intramuscularly or subcutaneously.
Effects usually start within 24 to 72 hours.
Maintenance doses may control symptoms for up to four weeks.
Careful monitoring and adjustments are needed for each patient.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
muscle rigiditydrowsinessdry mouthblurred visiontardive dyskinesia
Serious
neuroleptic malignant syndromesevere hypotension
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Warnings
⚠ Important warnings
- Increased risk of death in elderly patients with dementia-related psychosis.
- Tardive dyskinesia may develop and can be irreversible.
- Neuroleptic malignant syndrome can be fatal.
- Use cautiously in patients with known hypersensitivity to phenothiazines.
- Not approved for dementia-related psychosis.
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Drug interactions
- Benztropine Mesylatecontrols extrapyramidal symptomsCaution
- Intravenous Caffeine and Sodium Benzoate Injectioncontrols extrapyramidal symptoms.Caution
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Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).