MedDataToolGablofen is a medication used to help manage severe muscle stiffness and spasms in both adults and children aged 4 years and older. It works by calming the nerves in the spinal cord that cause these muscle issues. Gablofen is given through a pump that delivers it directly into the spinal fluid, starting with a screening dose of 50 micrograms, and the maximum daily dose can vary widely based on individual needs, typically ranging from 300 to 800 micrograms per day for spinal spasticity. It's important to know that Gablofen should not be used if you are allergic to baclofen. Additionally, if you are taking oral baclofen, your doctor may want to adjust or stop that medication before starting Gablofen to avoid possible overdose or side effects.
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Uses
- severe spasticity in adults. severe spasticity in children aged 4 and above.
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Dosage
Initial screening dose is 50 mcg for adults and children.
For children under 12, a 25 mcg dose may be tried first.
After screening, the dose may be adjusted based on response.
Continuous infusion is typically started after a positive screening response.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
Common side effects include somnolencedizzinessnauseaand headache
Serious
Serious side effects can include convulsionshypotoniaand hypotension
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Warnings
⚠ Important warnings
- Do not stop taking suddenly; it can cause severe reactions.
- Patients with spinal cord injuries at T-6 or above are at higher risk.
- Monitor for withdrawal symptoms if stopping treatment.
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Drug interactions
- Morphinecan cause hypotension and dyspneaCaution
Ask about this drug
Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).