MedDataToolGemfibrozil is a medication used to help lower high triglyceride levels in the blood, particularly in adults who are at risk for pancreatitis and haven't had enough success with diet alone. It works by reducing the amount of fat produced by the liver and increasing the levels of good cholesterol in the body. You take it in tablet form, with the usual starting dose being 1,200 mg per day, divided into two doses taken 30 minutes before meals, and this can go up to a maximum of 1,200 mg. A key warning is that it should not be used if you have severe liver or kidney problems, or gallbladder disease. Additionally, you should avoid taking gemfibrozil with simvastatin, as this combination can significantly increase the risk of serious muscle problems.
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Uses
- Very high triglyceride levels (over 2,000 mg/dL).
- Reducing risk of coronary heart disease in specific patients.
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Dosage
1,200 mg taken in two doses.
Take 30 minutes before morning and evening meals.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
Gastrointestinal issues like dyspepsia and abdominal painFatigue and nausea
Serious
Serious reactions like gallbladder disease and pancreatitis
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Warnings
⚠ Important warnings
- Not for patients with Type I hyperlipoproteinemia.
- Increased risk of gallbladder disease and surgery.
- May increase LDL-cholesterol in some patients.
- Caution with anticoagulants like warfarin.
- Not for use with simvastatin due to severe muscle risks.
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Drug interactions
- Warfarinincreased bleeding riskCaution
- Simvastatinincreased risk of muscle damageMonitor
Ask about this drug
Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).