MedDataToolGlyburide is a medication used to help adults with type 2 diabetes control their blood sugar levels, especially when diet and exercise alone aren't enough. It works by stimulating the pancreas to release more insulin, which helps lower blood sugar. You typically take it as a tablet once a day, starting with a dose of 2.5 to 5 mg, and the maximum recommended dose is 20 mg per day. It's important to know that glyburide is not suitable for people with type 1 diabetes or those who are allergic to it. Additionally, if you're taking colesevelam, you should take glyburide at least four hours before this medication, as it can affect how well glyburide works.
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Uses
- Type 2 diabetes mellitus.
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Dosage
Start with 2.5 to 5 mg daily with breakfast or the first main meal.
Patients sensitive to hypoglycemic drugs should start at 1.25 mg daily.
Adjust doses based on blood glucose response, usually in increments of 2.5 mg weekly.
Maximum daily dose is 20 mg.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
Nauseaheartburnepigastric fullnessHypoglycemiaBlood disorders like leukopenia and anemiaChanges in vision due to blood sugar fluctuations
Serious
Allergic skin reactions like itching and rashliver failurejaundice
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Warnings
⚠ Important warnings
- Not recommended for pregnant or pediatric patients.
- Use cautiously in elderly, malnourished, or patients with kidney/liver issues.
- May cause hypoglycemia if dosage is not followed.
- Monitor blood glucose regularly to avoid inadequate control.
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Drug interactions
- Colesevelamreduces glyburide effectivenessCaution
- Chlorpropamiderisk of hypoglycemia during transitionCaution
- Insulinmay require dose adjustment when switching.Caution
Ask about this drug
Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).