MedDataToolGocovri
Generic: Amantadine
Influenza A M2 Protein Inhibitor✓ FDA-verified
View full FDA label ↗Gocovri is a medication used to treat dyskinesia, which are involuntary movements, in people with Parkinson's disease who are also taking levodopa-based therapy. It works by affecting certain brain chemicals to help reduce these unwanted movements. You take it as a capsule once a day at bedtime, starting with a dose of 137 mg for the first week, then increasing to 274 mg. It's important to know that Gocovri should not be used by anyone with end-stage renal disease, as it can cause serious problems. Additionally, you should avoid drinking alcohol while taking this medication, as it can increase side effects like dizziness and confusion.
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Uses
- Dyskinesia in Parkinson's disease patients on levodopa therapy.
- Adjunctive treatment to levodopa/carbidopa for 'off' episodes in Parkinson's disease.
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Dosage
Start with 137 mg once daily at bedtime for one week.
After one week, increase to 274 mg once daily at bedtime.
Swallow capsules whole or sprinkle on soft food.
Can be taken with or without food.
Avoid alcohol while taking this medication.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
dizzinessdry mouthperipheral edemaconstipationfallsorthostatic hypotensionfalling asleep during daily activities
Serious
hallucinationssuicidalitydepressionhallucinationsconfusioncorneal edemaimpulse control issues
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Warnings
⚠ Important warnings
- Avoid sudden discontinuation to prevent adverse reactions.
- Not recommended for patients with end-stage renal disease.
- Use with caution in patients with moderate or severe renal impairment.
- May cause dizziness and confusion, especially with alcohol.
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Drug interactions
- Anticholinergic drugsmay increase side effectsCaution
- Drugs affecting urinary pHcan alter drug eliminationCaution
- Live attenuated influenza vaccinesmay interfere with vaccine effectivenessCaution
- Alcoholincreases risk of CNS effects.Monitor
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Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).