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Hydrochlorothiazide

Generic: Lisinopril And Hydrochlorothiazide Tablets

Rx only
ThiazidesAlso: Lisinopril and Hydrochlorothiazide✓ FDA-verified
View full FDA label ↗
Hydrochlorothiazide is a medication used to treat high blood pressure, helping to lower the risk of heart-related issues like strokes and heart attacks. It works by helping your body get rid of excess salt and water, which lowers blood pressure. Typically, it is taken as a tablet once a day, starting at a dose of 12.5 mg and can go up to a maximum of 50 mg daily. It's important to know that this medication should not be used if you are allergic to sulfonamide drugs. Additionally, if you are taking a medication called aliskiren and have diabetes, you should not take hydrochlorothiazide.
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Uses

  • Hypertension.
  • Lowering blood pressure.
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Dosage

Lisinopril: 10 mg to 80 mg once daily.
Hydrochlorothiazide: 12.5 mg to 50 mg once daily.
Combination therapy may be used if monotherapy is ineffective.
Adjust hydrochlorothiazide dose after 2-3 weeks if needed.
Always follow your doctor's specific instructions for your dose.
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Side effects

Common

dizzinessheadachecoughfatigueorthostatic effects

Serious

angioedemahypotensionrenal failureliver failure
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Warnings

⚠ Important warnings

  • Risk of angioedema, especially in Black patients.
  • Monitor for hypotension in patients on diuretics.
  • Not recommended for patients with severe renal impairment.
  • Discontinue if pregnancy is detected due to fetal toxicity.
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Drug interactions

  • Diureticsmay cause excessive blood pressure dropCaution
  • NSAIDsmay worsen kidney functionCaution
  • Lithiumrisk of toxicity increasesMonitor
  • Aliskirenavoid in diabetic patients.Avoid

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).