Hydrocodone

Generic: Hydrocodone Bitartrate And Acetaminophen

Rx only

Opioid✓ FDA-verified

Hydrocodone is a medication used to manage severe pain when other treatments haven't worked. It works by binding to specific receptors in the brain to reduce the feeling of pain. You can take it as a tablet, usually starting with 1 to 2 tablets every 4 to 6 hours as needed, but you shouldn't exceed 8 tablets in a day. It's important to know that this medication can be addictive, so it should only be used when necessary. Additionally, using hydrocodone with benzodiazepines, which are medications for anxiety or sleep issues, can increase the risk of serious breathing problems.

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Uses

Severe pain management.

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Dosage

5 mg/325 mg: 1–2 tablets every 4–6 hours as needed.. 7.5 mg/325 mg and 10 mg/325 mg: 1 tablet every 4–6 hours as needed.

Total daily dosage should not exceed 8 tablets for 5 mg/325 mg and 6 tablets for higher doses.

Always follow your doctor's specific instructions for your dose.

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Side effects

Common

light-headednessdizzinesssedationnauseavomitingrespiratory depression

Serious

allergic reactionssevere skin reactionsadrenal insufficiency

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Warnings

⚠ Important warnings

Risk of addiction, abuse, and misuse.
May cause life-threatening respiratory depression.
Accidental ingestion can be fatal, especially in children.
Use with benzodiazepines or CNS depressants increases risk of sedation and respiratory issues.
Not for patients with severe asthma or respiratory issues.

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Drug interactions

Benzodiazepinesincreased risk of sedation and respiratory depressionMonitor
CYP3A4 inhibitorsincreased hydrocodone effectsCaution
CYP3A4 inducersdecreased hydrocodone effectsCaution
Serotonergic drugsrisk of serotonin syndromeCaution
Mixed agonist/antagonist opioidsmay reduce effectiveness.Caution

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Answers pulled from the FDA label only.

Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).