MedDataToolMedDataTool

Hyoscyamine

Generic: Hyoscyamine Sulfate

Rx only
AnticholinergicAlso: Hyoscyamine ER✓ FDA-verified
View full FDA label ↗
Hyoscyamine is a medication used to help treat conditions like peptic ulcers, spastic colitis, and irritable bowel syndrome, among others. It works by blocking certain signals in the body that can cause muscle spasms and excessive secretions, helping to relieve symptoms. You take it as extended-release tablets, starting with 1 to 2 tablets every 12 hours, but you should not exceed 4 tablets in a 24-hour period. A key warning is that it can cause drowsiness, so you should avoid driving or operating heavy machinery while taking it. Additionally, it should not be used if you have glaucoma or certain gastrointestinal blockages.

Uses

  • Peptic ulcer.
  • Spastic colitis.
  • Spastic bladder.
  • Cystitis.
  • Pylorospasm.
  • Abdominal cramps.
  • Mild dysenteries.
  • Diverticulitis.
  • Acute enterocolitis.
  • Irritable bowel syndrome.
  • Neurogenic bladder.
  • Neurogenic bowel disturbances.
  • Biliary colic.
  • Renal colic.
  • Acute rhinitis.
  • Parkinsonism.

Dosage

1 to 2 tablets every 12 hours for adults.
Do not exceed 4 tablets in 24 hours.
Do not crush or chew tablets.
Always follow your doctor's specific instructions for your dose.

Side effects

Common

Dry mouthUrinary hesitancy and retentionBlurred visionTachycardiaPalpitationsHeadacheDrowsinessWeaknessFatigueDizzinessNauseaVomitingConstipationAbdominal painConfusionHallucinations

Serious

Allergic reactions
🛑

Warnings

⚠ Important warnings

  • Risk of heat prostration in high temperatures.
  • Diarrhea may indicate intestinal obstruction.
  • May cause drowsiness or dizziness.
  • Psychosis reported in sensitive individuals.
  • Use caution when operating machinery.
  • Not suitable for patients with ileostomy or colostomy.

Drug interactions

  • Other antimuscarinicsincreased side effectsCaution
  • Amantadineincreased side effectsCaution
  • Haloperidolincreased side effectsCaution
  • Phenothiazinesincreased side effectsCaution
  • MAO inhibitorsincreased side effectsCaution
  • Tricyclic antidepressantsincreased side effectsCaution
  • Some antihistaminesincreased side effectsCaution
  • Antacidsmay interfere with absorptionCaution

Ask about this drug

Answers pulled from the FDA label only.

AI
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).