MedDataToolImipramine pamoate is a medication used to help relieve symptoms of depression, particularly in adults. It works by affecting certain chemicals in the brain that help improve mood. You typically start with a dose of 75 mg per day, which can be increased to a maximum of 150 mg per day, and it can be taken once daily, preferably at bedtime. It's important to be aware that this medication can increase the risk of suicidal thoughts, especially in younger patients, so close monitoring is essential. Additionally, you should not take imipramine pamoate if you are currently using monoamine oxidase inhibitors (MAOIs), as this combination can lead to serious side effects.
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Uses
- Relief of symptoms of depression.
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Dosage
Outpatients: Start at 75 mg/day, may increase to 150 mg/day.
Hospitalized patients: Start at 100-150 mg/day, may increase to 200 mg/day.
Maintenance dose after remission: 75-150 mg/day.
Adolescents and elderly: Start at 25-50 mg/day, usually not exceeding 100 mg/day.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
Dry mouthblurred visionconstipationdrowsinessdizzinessHeart problems
Serious
hallucinationsseizuresallergic reactionsjaundice
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Warnings
⚠ Important warnings
- Increased risk of suicidal thoughts in children and young adults.
- Monitor for worsening depression or unusual behavior changes.
- Not approved for pediatric patients.
- Use caution in patients with cardiovascular disease.
- Avoid use with MAOIs like linezolid or methylene blue.
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Drug interactions
- Methylphenidatemay require dose adjustmentCaution
- Linezolidrisk of serotonin syndromeCaution
- Methylene bluerisk of serotonin syndrome.Caution
Ask about this drug
Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).