Invega Hafyera

Generic: Paliperidone Palmitate

Rx only

Atypical antipsychotic✓ FDA-verified

Invega Hafyera is a medication used to treat schizophrenia in adults who have been properly treated with other similar medications first. It works by affecting certain chemicals in the brain that help improve mood and behavior. This medication is given as an injection into the muscle every six months, with a starting dose based on previous treatments, ranging from 1,092 mg to 1,560 mg. It is important to know that Invega Hafyera should not be used if you are allergic to paliperidone or risperidone. Additionally, if you are taking carbamazepine, it may lower the effectiveness of Invega Hafyera, so be sure to discuss this with your healthcare provider.

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Uses

Treatment of schizophrenia in adults.

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Dosage

Administered as a gluteal injection once every 6 months by a healthcare professional.

Start INVEGA HAFYERA after adequate treatment with monthly or quarterly paliperidone injections.

Doses depend on previous paliperidone injection amounts.

Adjust dosage for patients with mild renal impairment before transitioning.

Always follow your doctor's specific instructions for your dose.

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Side effects

Common

Common side effects include upper respiratory tract infectioninjection site reactionsweight gainheadacheand parkinsonism

Serious

Serious side effects include increased mortality in elderly patients with dementia-related psychosisstrokeneuroleptic malignant syndromeand seizures

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Warnings

⚠ Important warnings

Increased risk of death in elderly patients with dementia-related psychosis.
Not approved for use in patients with dementia-related psychosis.
Not recommended for patients with moderate to severe renal impairment.
Monitor for orthostatic hypotension when used with other drugs that lower blood pressure.

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Drug interactions

Centrally acting drugsmay enhance CNS effectsCaution
Alcoholmay increase CNS effectsCaution
Strong CYP3A4 inducers (e.g., carbamazepine)may decrease paliperidone exposureCaution
Levodopamay reduce its effectiveness.Caution

Ask about this drug

Answers pulled from the FDA label only.

Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).