MedDataToolIsosorbide mononitrate is a medication used to prevent and treat chest pain caused by heart problems. It works by relaxing blood vessels, making it easier for blood to flow and reducing the heart's workload. You typically take it as a tablet, with a starting dose of 5 mg for smaller individuals, but most people take 20 mg twice a day, with doses spaced seven hours apart. It's important to know that you should not use this medication if you are allergic to it or if you are taking certain erectile dysfunction drugs like sildenafil, as this can lead to dangerously low blood pressure. Always talk to your doctor about your medications to ensure they are safe to use together.
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Uses
- Prevention of angina pectoris.
- Treatment of angina pectoris.
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Dosage
20 mg twice daily, doses 7 hours apart.
Starting dose may be 5 mg for small patients.
No dosage adjustments needed for elderly or those with liver or kidney issues.
Maintain a daily nitrate-free interval to avoid tolerance.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
Headachefatiguedizzinessnausea
Serious
Severe hypotensionallergic reactionscardiovascular disorders
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Warnings
⚠ Important warnings
- Do not use with sildenafil or riociguat.
- Monitor closely if used during heart attack or heart failure.
- Risk of severe low blood pressure with certain medications.
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Drug interactions
- Sildenafilrisk of severe hypotensionCaution
- RiociguatcontraindicatedAvoid
- Calcium channel blockersmay cause low blood pressureCaution
- Alcoholmay increase blood pressure effectsCaution
Ask about this drug
Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).