MedDataToolItraconazole oral solution is a medication used to treat infections in the mouth and esophagus caused by a type of fungus. It works by stopping the growth of the fungus, helping to clear the infection. You take it by swishing 10 mL in your mouth and swallowing it, with a typical starting dose of 200 mg (20 mL) daily for 1 to 2 weeks, or 100 mg (10 mL) twice a day if the infection does not respond to other treatments. A key warning is that it can cause serious liver problems, so if you notice any signs of liver issues, you should stop taking it and consult your doctor. Additionally, it should not be taken with certain heart medications like cisapride, as this can lead to dangerous heart rhythms.
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Uses
- Oropharyngeal candidiasis.
- Esophageal candidiasis.
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Dosage
200 mg (20 mL) daily for 1 to 2 weeks for oropharyngeal candidiasis.. 100 mg (10 mL) daily for at least three weeks for esophageal candidiasis.
For unresponsive oropharyngeal candidiasis, 100 mg (10 mL) twice daily.
Continue treatment for 2 weeks after symptoms resolve.
Take without food if possible.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
Nauseadiarrheavomitingabdominal painconstipation
Serious
Liver failurecardiac dysrhythmiassevere allergic reactions
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Warnings
⚠ Important warnings
- Risk of serious liver damage; discontinue if liver symptoms occur.
- Not for patients with heart issues unless benefits outweigh risks.
- Caution in patients with kidney or liver impairment.
- Do not use with certain drugs that can cause heart problems.
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Drug interactions
- Methadoneincreased risk of side effectsMonitor
- Disopyramideincreased risk of side effectsMonitor
- Dofetilideincreased risk of heart issuesMonitor
- Quinidineincreased risk of heart issuesMonitor
- Ergot alkaloidsincreased risk of side effects.Monitor
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Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).