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Januvia

Generic: Sitagliptin

Rx only
DPP-4 inhibitor✓ FDA-verified
View full FDA label ↗
Januvia is a medication used to help control blood sugar levels in adults with type 2 diabetes when combined with diet and exercise. It works by increasing the levels of certain hormones that help your body produce more insulin and lower blood sugar after meals. You take it as a pill, starting with a dose of 100 mg once a day, which can be adjusted to 50 mg or 25 mg daily if you have kidney problems. It's important to know that Januvia should not be used if you have a history of serious allergic reactions to it. Additionally, if you take insulin or certain other diabetes medications, you may have a higher risk of low blood sugar while using Januvia.

Uses

  • Type 2 diabetes mellitus.

Dosage

100 mg once daily for adults.
Can be taken with or without food.
For moderate kidney impairment, 50 mg once daily.
For severe kidney impairment, 25 mg once daily.
Always follow your doctor's specific instructions for your dose.

Side effects

Common

upper respiratory tract infectionnasopharyngitisheadachepancreatitis

Serious

heart failureacute renal failuresevere allergic reactions
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Warnings

⚠ Important warnings

  • Do not use in patients with type 1 diabetes.
  • Not studied in patients with a history of pancreatitis.
  • Monitor renal function before and during treatment.

Drug interactions

  • Insulin secretagoguesmay require lower doses to reduce hypoglycemia riskCaution
  • Insulinmay require lower doses to reduce hypoglycemia risk.Caution

Ask about this drug

Answers pulled from the FDA label only.

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).