MedDataToolKetorolac is a medication used to manage moderate to severe pain, often after surgery. It works by reducing substances in the body that cause pain and inflammation. It is typically given as an injection for the first few days, with a starting dose of 30 mg for adults under 65 and 15 mg for those 65 and older, and it should not be used for more than 5 days in total. A key warning is that it can cause serious stomach problems, including bleeding, especially in people with a history of ulcers. Additionally, it should not be taken with other nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin, as this can increase the risk of harmful side effects.
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Uses
- Moderately severe acute pain.
- Postoperative pain.
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Dosage
Intravenous or intramuscular dosing: 30 mg for patients under 65 years.
Intravenous or intramuscular dosing: 15 mg for patients 65 years or older.
Oral ketorolac is only for continuation after injection, not exceeding 5 days total.
Maximum daily dose: 120 mg for patients under 65 years; 60 mg for patients 65 years or older.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
abdominal painnauseavomitingheadachedizzinessgastrointestinal bleeding
Serious
renal failureanaphylactic reactionsliver failure
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Warnings
⚠ Important warnings
- Do not use for more than 5 days.
- Contraindicated in patients with active peptic ulcers or gastrointestinal bleeding.
- Increased risk of cardiovascular events, especially in patients with heart disease.
- Caution in elderly patients due to higher risk of serious side effects.
- Not for use in pediatric patients.
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Drug interactions
- Aspirinincreased risk of serious gastrointestinal eventsMonitor
- Morphinedo not mix in the same syringeAvoid
- Meperidinedo not mix in the same syringe.Avoid
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Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).