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Keytruda Qlex

Generic: Pembrolizumab And Berahyaluronidase Alfa-Pmph

Rx only
Glycoside Hydrolases✓ FDA-verified
View full FDA label ↗
Keytruda Qlex is a medication used to treat various types of cancer, including melanoma, non-small cell lung cancer, and certain other solid tumors. It works by helping the body's immune system recognize and fight cancer cells more effectively. This medication is given as a subcutaneous injection, typically every three weeks at a starting dose of 395 mg or every six weeks at 790 mg, depending on the treatment plan. It is important to know that Keytruda Qlex should not be used if you have a known allergy to its components, such as berahyaluronidase alfa. Additionally, patients taking other medications that suppress the immune system should discuss this with their healthcare provider, as it may affect how well Keytruda Qlex works.

Uses

  • Unresectable or metastatic melanoma.
  • Adjuvant treatment for Stage IIB, IIC, or III melanoma.
  • Metastatic non-small cell lung cancer (NSCLC).
  • Malignant pleural mesothelioma.
  • Head and neck squamous cell cancer (HNSCC).
  • Urothelial cancer.
  • Microsatellite instability-high or mismatch repair deficient cancer.
  • Advanced gastric cancer.
  • Esophageal cancer.
  • Cervical cancer.
  • Hepatocellular carcinoma.
  • Biliary tract cancer.
  • Merkel cell carcinoma.
  • Renal cell carcinoma.
  • Endometrial carcinoma.
  • Tumor mutational burden-high cancer.
  • Cutaneous squamous cell carcinoma.
  • Triple-negative breast cancer.
  • Ovarian cancer.

Dosage

395 mg/4,800 units every 3 weeks. 790 mg/9,600 units every 6 weeks.
Administer subcutaneously in the thigh or abdomen.
Always follow your doctor's specific instructions for your dose.

Side effects

Common

nauseafatiguemusculoskeletal painpneumonitis

Serious

colitishepatitissevere allergic reactions
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Warnings

⚠ Important warnings

  • Severe immune-mediated reactions may occur.
  • Not for patients with active autoimmune diseases.
  • Use with caution in patients with liver problems.

Drug interactions

  • Axitinibincreased risk of liver problemsMonitor
  • Lenvatinibincreased risk of liver problemsMonitor

Ask about this drug

Answers pulled from the FDA label only.

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).