Lansoprazole is a medication used to treat various stomach and esophagus conditions, including ulcers, gastroesophageal reflux disease (GERD), and to help eliminate H. pylori bacteria that can cause ulcers. It works by reducing the amount of acid your stomach produces, which helps heal these conditions and relieve symptoms. You typically take it as a delayed-release capsule, starting with a dose of 15 mg to 30 mg once daily, depending on your specific condition, and you should not exceed 60 mg per day. It's important to know that if you are allergic to any ingredient in this medication, you should not take it. Additionally, lansoprazole should not be taken with rilpivirine-containing products, as this combination can lead to serious interactions.
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Uses
- Active duodenal ulcer in adults.
- Eradication of H. pylori to reduce duodenal ulcer recurrence in adults.
- Maintenance of healed duodenal ulcers in adults.
- Active benign gastric ulcer in adults.
- NSAID-associated gastric ulcer in adults.
- Symptomatic gastroesophageal reflux disease (GERD) in adults and pediatric patients 1 year and older.
- Erosive esophagitis (EE) in adults and pediatric patients 1 year and older.
- Maintenance of healing of EE in adults.
- Pathological hypersecretory conditions, including Zollinger-Ellison Syndrome in adults.
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Dosage
15 mg once daily for duodenal ulcers. 30 mg once daily for benign gastric ulcers. 15 mg once daily for maintenance of healed ulcers.
Take before meals.
Do not crush or chew capsules.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
diarrheaabdominal painnauseaconstipationacute tubulointerstitial nephritis
Serious
Clostridium difficile-associated diarrheabone fracturesevere cutaneous adverse reactions
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Warnings
⚠ Important warnings
- Contraindicated with rilpivirine, nelfinavir.
- May increase INR and prothrombin time with warfarin.
- Caution in patients with severe liver impairment.
- May cause false positive results in neuroendocrine tumor tests.
- Monitor for hypomagnesemia and vitamin B-12 deficiency.
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Drug interactions
- Warfarinincreased bleeding riskCaution
- Methotrexatemay elevate serum concentrationsCaution
- Digoxinpotential increased exposureCaution
- Theophyllineincreased clearanceCaution
- Sucralfatedelayed absorption of lansoprazoleCaution
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Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
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