Lialda is a medication used to treat mildly to moderately active ulcerative colitis in adults and children who weigh at least 24 kg. It works by reducing inflammation in the colon, helping to manage symptoms and maintain remission. The medication comes in tablet form and is usually taken once daily, with a starting dose of 2.4 grams (two 1.2-gram tablets) and a maximum dose of 4.8 grams (four 1.2-gram tablets). It's important to know that Lialda should not be taken if you are allergic to salicylates or aminosalicylates. Additionally, if you are taking sulfamethoxazole/trimethoprim, be aware that it may interact with Lialda, leading to increased levels of the antibiotic in your body.
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Uses
- mildly to moderately active ulcerative colitis in adults. mildly to moderately active ulcerative colitis in pediatric patients weighing at least 24 kg.
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Dosage
Adults: 2.4 g to 4.8 g once daily for induction of remission.
Adults: 2.4 g once daily for maintenance of remission.
Pediatric patients (24 kg to 35 kg): 2.4 g once daily for 8 weeks, then 1.2 g once daily.
Pediatric patients (greater than 35 kg to 50 kg): 3.6 g once daily for 8 weeks, then 2.4 g once daily.
Pediatric patients (greater than 50 kg): 4.8 g once daily for 8 weeks, then 2.4 g once daily.
Swallow tablets whole with food and drink plenty of fluids.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
headacheflatulenceabdominal paindiarrheaPediatric common: abdominal painupper respiratory tract infectionvomitinganemiaheadacheviral infectionrenal impairment
Serious
liver function test abnormalhypersensitivity reactionshepatic failuresevere skin reactions
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Warnings
⚠ Important warnings
- Monitor renal function before and during treatment.
- Risk of renal failure and nephrotoxicity with certain medications.
- Increased risk of blood disorders with azathioprine or 6-mercaptopurine.
- May cause acute intolerance syndrome and hypersensitivity reactions.
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Drug interactions
- Nephrotoxic Agentsincreased risk of kidney damageMonitor
- Azathioprineincreased risk of blood disordersMonitor
- 6-Mercaptopurineincreased risk of blood disorders.Monitor
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Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
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