MedDataToolLIKMEZ is an antibiotic used to treat infections caused by certain bacteria and parasites, including trichomoniasis, amebiasis, and serious anaerobic bacterial infections. It works by entering the bacteria or parasites and disrupting their DNA, which helps to kill them. The medication can be taken orally, with a common starting dose for trichomoniasis being either 2 grams in one dose or 250 mg three times a day for seven days. It's important to avoid alcohol during treatment and for at least three days after, as it can cause unpleasant reactions. Additionally, if you've taken disulfiram in the last two weeks, you should not use this medication.
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Uses
- Trichomoniasis in adults.
- Amebiasis in adults and pediatric patients.
- Anaerobic bacterial infections in adults.
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Dosage
Trichomoniasis: 2 g as a single dose or 250 mg three times daily for 7 days.
Amebiasis: 750 mg three times daily for 5 to 10 days.
Pediatric patients: 35-50 mg/kg per day divided into three doses.
For severe liver impairment, reduce dose by 50%.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
nauseaheadachevomitingdiarrheaabdominal cramping
Serious
seizuresencephalopathyoptic neuropathyliver failure
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Warnings
⚠ Important warnings
- Potential for carcinogenicity; avoid unnecessary use.
- Contraindicated with disulfiram and alcohol.
- Monitor anticoagulant effects with warfarin.
- Use caution in patients with severe liver impairment.
- Consider dose adjustment in patients undergoing hemodialysis.
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Drug interactions
- Disulfiramrisk of psychotic reactionsCaution
- Alcoholabdominal cramps and nauseaCaution
- Warfarinincreased bleeding riskCaution
- Lithiumelevated serum levelsCaution
- Busulfanincreased toxicity riskCaution
Ask about this drug
Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).