Lisinopril is a medication used to treat high blood pressure, heart failure, and to help reduce the risk of death after a heart attack. It works by relaxing blood vessels, making it easier for the heart to pump blood. You typically take it as a tablet once a day, starting with a dose of 10 mg, which can be increased to a maximum of 40 mg based on your blood pressure response. It's important to know that you should not take lisinopril if you have a history of severe allergic reactions called angioedema. Additionally, if you are taking a medication called aliskiren and have diabetes, you should not use lisinopril.
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Uses
- Hypertension in adults and children 6 years and older.
- Heart failure.
- Acute myocardial infarction.
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Dosage
Adults: Start with 10 mg once daily, adjust based on blood pressure response.
Children 6 years and older: Start with 0.07 mg per kg once daily (up to 5 mg).
For heart failure: Start with 5 mg once daily, increase as tolerated.
For acute myocardial infarction: Start with 5 mg within 24 hours, then adjust.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
Headachedizzinesscoughchest painAcute myocardial infarction: Low blood pressureKidney problems
Serious
Heart failure: Low blood pressureallergic reactions
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Warnings
⚠ Important warnings
- Can cause fetal toxicity; discontinue if pregnancy is detected.
- May cause low blood pressure, especially in patients on diuretics.
- Monitor for kidney function and potassium levels.
- Risk of angioedema with certain medications.
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Drug interactions
- Diureticsmay cause excessive drop in blood pressureCaution
- NSAIDsincreased risk of kidney problemsMonitor
- Lithiumrisk of lithium toxicityCaution
- Goldmay cause nitritoid reactionsCaution
- mTOR inhibitorsincreased risk of angioedema.Monitor
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Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
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