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Lisinopril

Rx only
ACE inhibitor✓ FDA-verified
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Lisinopril is a medication used to treat high blood pressure, heart failure, and to help reduce the risk of death after a heart attack. It works by relaxing blood vessels, making it easier for the heart to pump blood. You typically take it as a tablet once a day, starting with a dose of 10 mg, which can be increased to a maximum of 40 mg based on your blood pressure response. It's important to know that you should not take lisinopril if you have a history of severe allergic reactions called angioedema. Additionally, if you are taking a medication called aliskiren and have diabetes, you should not use lisinopril.

Uses

  • Hypertension in adults and children 6 years and older.
  • Heart failure.
  • Acute myocardial infarction.

Dosage

Adults: Start with 10 mg once daily, adjust based on blood pressure response.
Children 6 years and older: Start with 0.07 mg per kg once daily (up to 5 mg).
For heart failure: Start with 5 mg once daily, increase as tolerated.
For acute myocardial infarction: Start with 5 mg within 24 hours, then adjust.
Always follow your doctor's specific instructions for your dose.

Side effects

Common

Headachedizzinesscoughchest painAcute myocardial infarction: Low blood pressureKidney problems

Serious

Heart failure: Low blood pressureallergic reactions
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Warnings

⚠ Important warnings

  • Can cause fetal toxicity; discontinue if pregnancy is detected.
  • May cause low blood pressure, especially in patients on diuretics.
  • Monitor for kidney function and potassium levels.
  • Risk of angioedema with certain medications.

Drug interactions

  • Diureticsmay cause excessive drop in blood pressureCaution
  • NSAIDsincreased risk of kidney problemsMonitor
  • Lithiumrisk of lithium toxicityCaution
  • Goldmay cause nitritoid reactionsCaution
  • mTOR inhibitorsincreased risk of angioedema.Monitor

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Answers pulled from the FDA label only.

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).