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Lorazepam

Rx only
Benzodiazepines✓ FDA-verified
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Lorazepam is a medication used to help manage anxiety disorders and provide short-term relief from anxiety symptoms. It works by calming the brain and nervous system. You take it as a tablet, usually starting with a dose of 2 to 3 mg per day, which can be increased up to a maximum of 10 mg per day based on your doctor's advice. It's important to know that using lorazepam with opioids can lead to serious risks, including severe sedation and breathing problems. Additionally, if you have a sensitivity to benzodiazepines or acute narrow-angle glaucoma, you should not take this medication.

Uses

  • Anxiety disorders.
  • Short-term relief of anxiety symptoms.
  • Anxiety associated with depressive symptoms.

Dosage

Adults usually start with 2 to 3 mg daily, divided into two or three doses.
For insomnia due to anxiety, take 2 to 4 mg at bedtime.
Elderly patients should start with 1 to 2 mg daily, adjusted as needed.
Gradually increase the dose to avoid side effects.
Always follow your doctor's specific instructions for your dose.

Side effects

Common

sedationdizzinessweaknessunsteadinessrespiratory depression

Serious

seizuresconfusionsuicidal thoughts
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Warnings

⚠ Important warnings

  • Risk of severe sedation and respiratory depression when used with opioids.
  • Potential for abuse, misuse, and addiction.
  • Physical dependence can occur with long-term use.
  • Abruptly stopping may cause life-threatening withdrawal reactions.
  • Not recommended for patients with primary depressive disorders.

Drug interactions

  • Opioidsincreased risk of sedation and respiratory depressionMonitor
  • Alcoholenhanced sedative effectsCaution
  • Clozapinemay cause excessive sedation and respiratory arrestCaution
  • Valproateincreases lorazepam levels, may require dose reductionMonitor
  • Probenecidmay prolong lorazepam effects, may require dose reduction.Caution

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Answers pulled from the FDA label only.

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).