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Losartan

Generic: Losartan Potassium

Rx only
Angiotensin II receptor blocker✓ FDA-verified
View full FDA label ↗
Losartan is a medication used to treat high blood pressure in adults and children over 6 years old, and it can also help protect the kidneys in people with type 2 diabetes. It works by blocking a substance in the body that causes blood vessels to tighten, which helps relax the blood vessels and lower blood pressure. You typically take it as a tablet once a day, starting with a dose of 50 mg, which can be increased to a maximum of 100 mg if needed. It's important to know that losartan should not be taken if you are allergic to it or its ingredients. Additionally, if you are taking a medication called aliskiren and have diabetes, you should not use losartan.

Uses

  • Treatment of hypertension in adults and children over 6 years old.
  • Reduction of stroke risk in patients with hypertension and left ventricular hypertrophy.
  • Treatment of diabetic nephropathy in type 2 diabetes patients with hypertension.

Dosage

Adults: 50 mg once daily, can increase to 100 mg if needed.
Children: 0.7 mg per kg once daily, up to 50 mg.
For patients with mild to moderate liver issues: start with 25 mg once daily.
Always follow your doctor's specific instructions for your dose.

Side effects

Common

dizzinessupper respiratory infectionnasal congestionback pain

Serious

angioedemahypotensionliver issueskidney impairment
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Warnings

⚠ Important warnings

  • Fetal toxicity: discontinue if pregnancy is detected.
  • Not recommended for patients with severe liver impairment.
  • Monitor potassium levels if taking with potassium-increasing drugs.
  • Risk of lithium toxicity when taken with lithium.
  • NSAIDs may worsen kidney function when taken with losartan.

Drug interactions

  • Potassium-increasing drugsrisk of hyperkalemiaCaution
  • Lithiumrisk of lithium toxicityCaution
  • NSAIDsincreased risk of kidney problemsMonitor
  • Aliskirenavoid in diabetes patientsAvoid

Ask about this drug

Answers pulled from the FDA label only.

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).