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Loxapine

Rx only
Antipsychotic✓ FDA-verified
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Loxapine is a medication used to treat schizophrenia, a mental health condition that affects how a person thinks, feels, and behaves. It works by calming certain areas of the brain to help reduce symptoms of the illness. You usually take it in capsule form, two to four times a day, starting with a dose of 10 mg twice daily, which can be increased based on your needs, but should not exceed 250 mg daily. It's important to know that loxapine is not safe for people who are in a coma or have severe depression caused by drugs like alcohol or narcotics. Additionally, elderly patients with dementia-related psychosis should avoid this medication due to an increased risk of serious side effects.

Uses

  • Schizophrenia.

Dosage

Initial dose is 10 mg twice daily.
Dosage can be adjusted based on symptoms.
Usual maintenance dose is 60 to 100 mg daily.
Dosage higher than 250 mg is not recommended.
Always follow your doctor's specific instructions for your dose.

Side effects

Common

Drowsinessdizzinessmuscle twitchinginsomniaTardive dyskinesia

Serious

neuroleptic malignant syndromeseizures
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Warnings

⚠ Important warnings

  • Increased risk of death in elderly patients with dementia-related psychosis.
  • Risk of tardive dyskinesia with long-term use.
  • Neuroleptic malignant syndrome can be fatal.
  • May impair mental and physical abilities.
  • Risk of falls due to drowsiness and instability.

Drug interactions

  • Lorazepamrisk of respiratory depression and hypotension.Caution

Ask about this drug

Answers pulled from the FDA label only.

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).