MedDataToolLyllana is a medication that contains estrogen and is used to treat moderate to severe hot flashes during menopause and to help prevent osteoporosis after menopause. It works by replacing the estrogen that the body no longer produces, which helps to manage these symptoms. You apply it as a patch to your skin twice a week, starting with a dose of 0.0375 mg for hot flashes or 0.025 mg for osteoporosis, and the dose can be adjusted based on how you respond to the treatment. It's important to know that Lyllana should not be used if you have a history of breast cancer or certain blood clots. Additionally, if you are taking medications that affect blood clotting, like warfarin, you should discuss this with your doctor, as it may interact with Lyllana.
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Uses
- Moderate to severe vasomotor symptoms due to menopause.
- Prevention of postmenopausal osteoporosis.
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Dosage
Start with 0.0375 mg per day for vasomotor symptoms, applied to the skin twice weekly.
Start with 0.025 mg per day for osteoporosis prevention, applied to the skin twice weekly.
Replace the patch every 3 to 4 days.
Apply to clean, dry skin on the lower abdomen or buttocks.
Do not apply to the breasts.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
headachebreast tendernessback painlimb painnasopharyngitisdyspepsianauseasinusitisintermenstrual bleedingincreased risk of endometrial cancer
Serious
cardiovascular disordersprobable dementiaand breast cancer
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Warnings
⚠ Important warnings
- Increased risk of endometrial cancer for women with a uterus using unopposed estrogens.
- Increased risk of stroke and deep vein thrombosis in postmenopausal women.
- Increased risk of probable dementia in women 65 and older.
- Do not use for preventing cardiovascular disease or dementia.
- Consider non-estrogen medications for osteoporosis prevention first.
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Drug interactions
- John's wortmay reduce estrogen effectivenessCaution
- Phenobarbitalmay reduce estrogen effectivenessCaution
- Carbamazepinemay reduce estrogen effectivenessCaution
- Rifampinmay reduce estrogen effectivenessCaution
- Erythromycinmay increase estrogen levelsCaution
- Grapefruit juicemay increase estrogen levels.Caution
Ask about this drug
Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).