MedDataToolMagnesium Sulfate in Dextrose is a medication used to prevent and treat seizures in pregnant women with conditions like preeclampsia and eclampsia. It works by calming the nervous system and reducing muscle contractions to help stop seizures. This medication is given through an intravenous (IV) line, starting with a dose of 4 to 6 grams over 15 minutes, followed by 1 to 2 grams every hour, with a maximum of 30 to 40 grams in 24 hours. It should not be used in patients with heart block or severe kidney problems. Additionally, it can interact with certain medications, such as salicylates, which should not be given through the same IV line.
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Uses
- Prevention of eclampsia in patients with preeclampsia.
- Treatment of seizures in patients with eclampsia.
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Dosage
Initial dose: 4 to 6 grams over 15 minutes.
Maintenance dose: 1 to 2 grams every hour.
Maximum dose: 30 to 40 grams over 24 hours.
Monitor magnesium levels and adjust as needed.
Do not use for more than 5 to 7 days.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
flushingsweatinglow blood pressuredepressed reflexesrespiratory paralysis
Serious
cardiac depressionvisual disturbanceslethargy
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Warnings
⚠ Important warnings
- Not recommended for use beyond 5 to 7 days.
- Use caution in patients with severe kidney problems.
- Do not mix with incompatible drugs like salicylates.
- Monitor for signs of magnesium toxicity.
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Drug interactions
- Neuromuscular Blocking Agentsmay increase muscle relaxation effectsCaution
- Narcotics and/or Propofolmay enhance sedation effectsCaution
- Dihydropyridine Calcium Channel Blockersmay cause low blood pressureCaution
- Drugs that may induce magnesium lossmay reduce effectiveness.Caution
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Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).