Methimazole is a medication used to treat hyperthyroidism, a condition where the thyroid gland is overactive. It works by reducing the amount of thyroid hormones produced by the thyroid gland. You typically take it as a tablet, starting with a dose of 15 to 60 milligrams per day, which can be adjusted based on your needs, but you should not exceed 120 milligrams daily. A key warning is that it can cause serious side effects like agranulocytosis, a condition that affects your white blood cells, so you should report any signs of fever or sore throat to your doctor immediately. Additionally, if you are pregnant or planning to become pregnant, it's important to discuss this with your doctor, as the medication can affect the fetus.
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Uses
- Hyperthyroidism.
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Dosage
- Follow your doctor's specific instructions for your dose.
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Side effects
Common
FeverSore throatAnorexiaPruritusRight upper quadrant painHypothyroidism
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Warnings
⚠ Important warnings
- Can cause fetal harm if used in the first trimester of pregnancy.
- Risk of congenital defects in infants if used during early pregnancy.
- Agranulocytosis can be life-threatening; report fever or sore throat.
- Liver toxicity may occur; monitor liver function.
- Methimazole can cause hypothyroidism; monitor TSH and free T4 levels.
- Vasculitis may occur; discontinue if suspected.
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Drug interactions
- Oral anticoagulantsmay increase bleeding riskCaution
- Beta blockersmay need dose reductionCaution
- Digitalis glycosidesmay increase serum levelsCaution
- Theophyllinemay need dose reductionCaution
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Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
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