MedDataToolMirtazapine is a medication used to treat major depressive disorder in adults. It works by balancing certain chemicals in the brain that affect mood, helping to improve feelings of sadness and anxiety. You take it as a tablet once a day, preferably in the evening, starting with a dose of 15 mg, which can be increased to a maximum of 45 mg if needed. It's important to know that you should not take mirtazapine if you have recently stopped taking a type of antidepressant called MAOIs, as this can lead to serious side effects. Additionally, if you are taking strong medications that affect liver enzymes, like carbamazepine or phenytoin, your doctor may need to adjust your dose of mirtazapine.
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Uses
- Major depressive disorder (MDD) in adults.
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Dosage
Start with 15 mg once daily.
May increase to a maximum of 45 mg once daily.
Take the medication orally in the evening before sleep.
Gradually reduce the dose when stopping the medication.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
Common side effects include drowsinessincreased appetiteweight gainand dizziness
Serious
Serious side effects may include suicidal thoughtsseizuresand severe allergic reactions
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Warnings
⚠ Important warnings
- Increased risk of suicidal thoughts in young adults and children.
- Not approved for use in pediatric patients.
- Screen for bipolar disorder before starting treatment.
- Avoid use with monoamine oxidase inhibitors (MAOIs).
- Monitor for serotonin syndrome with other serotonergic drugs.
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Drug interactions
- MAOIsrisk of serotonin syndromeCaution
- Strong CYP3A inducersmay need higher mirtazapine doseCaution
- Strong CYP3A inhibitorsmay need lower mirtazapine doseCaution
- Cimetidinemay increase mirtazapine levelsCaution
- Warfarinmonitor INR levels.Monitor
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Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).