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Natazia

Generic: Estradiol Valerate And Estradiol Valerate/Dienogest

Rx only
Combination oral contraceptive✓ FDA-verified
View full FDA label ↗
Natazia is a medication that combines two hormones, dienogest and estradiol valerate, to help prevent pregnancy and treat heavy menstrual bleeding in women. It works by stopping the ovaries from releasing eggs, which helps to prevent pregnancy. You take it as a tablet, one each day at the same time, starting on the first day of your menstrual cycle, and you should not skip or delay taking it by more than 12 hours. A key warning is that it should not be used by women who have a high risk of blood clots, such as those who smoke and are over 35 years old. Additionally, if you are taking certain medications like rifampin, it may reduce the effectiveness of Natazia, so it's important to discuss any other drugs you are using with your healthcare provider.

Uses

  • Prevent pregnancy.
  • Treat heavy menstrual bleeding.

Dosage

Take one tablet daily at the same time.
Follow the order on the blister pack.
Do not skip or delay taking by more than 12 hours.
Start on the first day of your menstrual cycle.
Use a non-hormonal backup method for the first 9 days.
Always follow your doctor's specific instructions for your dose.

Side effects

Common

Headache (including migraines)Breast pain or tendernessMenstrual disordersNausea or vomitingAcneMood changesIncreased weight
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Warnings

⚠ Important warnings

  • Do not use if you smoke and are over 35 years old.
  • Increased risk of serious cardiovascular events.
  • Not evaluated for women with BMI over 30.
  • Consult your doctor if you have liver disease.

Drug interactions

  • Rifampindecreases effectiveness of NataziaCaution
  • Phenytoinmay reduce contraceptive effectivenessCaution
  • Carbamazepinemay reduce contraceptive effectivenessCaution
  • John's wortmay reduce contraceptive effectivenessCaution
  • Ketoconazoleincreases hormone levelsMonitor
  • Erythromycinincreases hormone levelsMonitor

Ask about this drug

Answers pulled from the FDA label only.

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).