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Nebivolol

Rx only
Beta-blocker✓ FDA-verified
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Nebivolol is a medication used to treat high blood pressure, which helps lower the risk of serious heart problems like strokes and heart attacks. It works by blocking certain receptors in the heart, which can help slow down the heart rate and relax blood vessels, making it easier for blood to flow. You typically take it as a tablet once a day, starting with a dose of 5 mg, which can be increased to a maximum of 40 mg if needed. It's important to know that this medication should not be taken if you have severe liver problems or a very slow heart rate. Additionally, if you are taking medications that affect liver enzymes, like fluoxetine, your doctor may need to adjust your dose of nebivolol.

Uses

  • Hypertension.

Dosage

Start with 5 mg once daily.
Can be taken with or without food.
Dose can be increased every 2 weeks up to 40 mg.
For severe kidney issues, start at 2.5 mg once daily.
For moderate liver issues, start at 2.5 mg once daily.
Always follow your doctor's specific instructions for your dose.

Side effects

Common

headachefatiguebradycardiaMay cause diarrhea and chest painPossible skin rash and insomniaMonitor for any unusual symptoms

Serious

nauseadizziness
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Warnings

⚠ Important warnings

  • Not recommended for severe liver impairment.
  • Use caution with CYP2D6 inhibitors.
  • Avoid combining with other beta-blockers.
  • Monitor closely with reserpine or clonidine.
  • Risk of bradycardia with digitalis glycosides.

Drug interactions

  • CYP2D6 inhibitorsmay increase nebivolol levelsCaution
  • Reserpinemay cause excessive reduction of sympathetic activityCaution
  • Clonidinediscontinue nebivolol before taperingCaution
  • Digitalis glycosidesincreased risk of bradycardiaMonitor
  • Calcium channel blockersmay worsen heart rate and blood pressure.Caution

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Answers pulled from the FDA label only.

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).