Nitroglycerin in Dextrose is a medication used to treat high blood pressure during surgery, heart failure after a heart attack, and chest pain that doesn't respond to other treatments. It works by relaxing blood vessels, which helps improve blood flow and reduces the heart's workload. This medication is given through an IV, starting with a dose of 5 micrograms per minute, which can be adjusted based on how the patient responds, with higher doses possible if needed. It's important to note that this medication should not be used in patients who are allergic to it or those with certain heart conditions. Additionally, it should not be taken with medications for erectile dysfunction, as this can lead to dangerously low blood pressure.
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Uses
- Peri-operative hypertension.
- Heart failure during acute myocardial infarction.
- Angina pectoris not responding to other treatments.
- Induction of intraoperative hypotension.
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Dosage
Administered through an IV infusion pump.
Initial adult dose is 5 mcg/min.
Adjust dose based on patient response.
Monitor blood pressure and heart rate continuously.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
LightheadednessHypotensionSyncopeCrescendo anginaRebound hypertension
Serious
Severe headache
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Warnings
⚠ Important warnings
- Use of PVC tubing may reduce drug effectiveness.
- Avoid mixing with other medications.
- Risk of fluid overload.
- Do not use with phosphodiesterase inhibitors.
- Monitor for allergic reactions.
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Drug interactions
- Sildenafilcan cause low blood pressureCaution
- Tadalafilcan cause low blood pressureCaution
- Vardenafilcan cause low blood pressureCaution
- Riociguatcan cause low blood pressureCaution
- Calcium channel blockersmay cause orthostatic hypotensionCaution
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Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
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