MedDataToolNitroglycerin Transdermal Infusion System
Generic: Nitroglycerin
Nitrate✓ FDA-verified
View full FDA label ↗Nitroglycerin Transdermal Infusion System is a patch used to help prevent chest pain (angina) caused by heart problems. It works by relaxing blood vessels, making it easier for blood to flow and reducing the heart's workload. You typically start with a dose of 0.2 to 0.4 mg per hour, and the maximum dose can go up to 0.8 mg per hour, with the patch worn for 12 to 14 hours each day and then taken off for 10 to 12 hours to avoid tolerance. It's important to know that you should not use this medication if you're allergic to it or if you're taking certain medications for erectile dysfunction, like sildenafil, as this can cause dangerously low blood pressure.
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Uses
- Prevention of angina pectoris due to coronary artery disease.
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Dosage
Starting dose is 0.2 mg/hr to 0.4 mg/hr.
Doses of 0.4 mg/hr to 0.8 mg/hr can be effective for 10 to 12 hours daily.
Use a patch for 12 to 14 hours each day.
Have a drug-free period of 10 to 12 hours daily.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
Headaches may occur with each doseespecially at higher doses
Serious
Common side effects include severe headache and lightheadednessHypotension may happen but is rareSerious side effects like syncope and rebound hypertension are uncommonAllergic reactions are rare but can include skin irritation
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Warnings
⚠ Important warnings
- Consult your doctor before using this drug.
- Avoid using with phosphodiesterase inhibitors like sildenafil due to severe hypotension risk.
- Careful monitoring is needed if used during acute myocardial infarction or congestive heart failure.
- Do not discharge a defibrillator through a patch.
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Drug interactions
- Sildenafilmay cause severe hypotensionCaution
- Riociguatcontraindicated with nitroglycerinAvoid
Ask about this drug
Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).