MedDataToolOnureg is a medication used for the ongoing treatment of adults with acute myeloid leukemia who have achieved a certain level of remission after initial chemotherapy but cannot continue with more intensive treatment. It works by interfering with the way cancer cells grow and multiply, helping to slow down or stop their progression. You take it as a tablet, swallowing it whole once a day at a dose of 300 mg for the first 14 days of each 28-day cycle, and the maximum dose is also 300 mg. It's important to know that Onureg should not be used if you have a severe allergy to azacitidine or its components. Additionally, if you are taking omeprazole, a common heartburn medication, it may increase the levels of Onureg in your body, so be sure to discuss this with your doctor.
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Uses
- acute myeloid leukemia.
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Dosage
Take 300 mg orally once daily for Days 1 through 14 of each 28-day cycle.
Do not substitute for intravenous or subcutaneous azacitidine.
Take with or without food.
If you miss a dose, take it as soon as possible on the same day.
Do not take 2 doses on the same day.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
nauseavomitingdiarrheafatigueconstipationupper respiratory infectionpneumonia
Serious
febrile neutropeniadizzinessskin infectionabdominal pain
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Warnings
⚠ Important warnings
- Do not use if neutrophil count is less than 0.5 Gi/L.
- Monitor blood counts every other week for the first 2 cycles.
- Hazardous drug; follow special handling and disposal procedures.
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Drug interactions
- Omeprazoleincreases azacitidine levels.Monitor
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Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).