MedDataToolMedDataTool

Oseni

Generic: Alogliptin And Pioglitazone

Rx only
DPP-4 inhibitor and thiazolidinedione✓ FDA-verified
View full FDA label ↗
Oseni is a medication used to help adults with type 2 diabetes manage their blood sugar levels, especially when diet and exercise alone aren't enough. It combines two active ingredients that work together: one helps increase insulin release when you eat, and the other makes your body more sensitive to insulin. You take it as a pill once a day, starting with a dose of 25 mg of alogliptin and 15 mg of pioglitazone, and you shouldn't exceed 25 mg of alogliptin and 45 mg of pioglitazone daily. It's important to know that Oseni is not recommended for people with severe heart failure. Additionally, if you are taking gemfibrozil, a cholesterol-lowering medication, the maximum dose of Oseni should be 25 mg of alogliptin and 15 mg of pioglitazone.
✦

Uses

  • Type 2 diabetes mellitus.
◷

Dosage

Take OSENI once daily, with or without food.
Starting dose is based on current medications.
Do not exceed 25 mg of alogliptin and 45 mg of pioglitazone daily.
Monitor liver tests before starting OSENI.
Assess kidney function before starting OSENI.
Always follow your doctor's specific instructions for your dose.
⚠

Side effects

Common

nasopharyngitisback painupper respiratory tract infectionedemafracturesurinary bladder tumorshypoglycemia when used with insulin or insulin secretagogues

Serious

congestive heart failurepancreatitishypersensitivity reactionsliver effects
🛑

Warnings

⚠ Important warnings

  • May cause or worsen congestive heart failure.
  • Not recommended for patients with type 1 diabetes.
  • Use caution in patients with liver disease.
  • Monitor for fluid retention and heart failure symptoms.
⇄

Drug interactions

  • Gemfibrozilincreases pioglitazone levelsMonitor
  • Rifampinmay decrease pioglitazone levelsCaution
  • Topiramatemay decrease pioglitazone levelsCaution
  • Insulin secretagoguesmay increase risk of hypoglycemia.Caution

Ask about this drug

Answers pulled from the FDA label only.

AI
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).