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Ozempic

Generic: Oral Semaglutide

Rx only
GLP-1 receptor agonistAlso: RYBELSUS✓ FDA-verified
View full FDA label ↗
Ozempic is a medication used to help adults with type 2 diabetes manage their blood sugar levels and reduce the risk of serious heart problems. It works by helping your body release more insulin when blood sugar is high and lowering the amount of sugar your liver makes. You take it as a tablet once a day on an empty stomach, starting with a dose of 1.5 mg for the first 30 days, which can be increased to a maximum of 9 mg if more blood sugar control is needed. It’s important to know that this medication should not be used if you have a personal or family history of certain thyroid cancers. Additionally, if you take insulin or medications that increase insulin, you may be at a higher risk for low blood sugar when using Ozempic.
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Uses

  • Type 2 diabetes mellitus.
  • Reduce risk of major cardiovascular events in high-risk adults.
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Dosage

RYBELSUS: Start with 3 mg daily for 30 days, then increase to 7 mg.
OZEMPIC: Start with 1.5 mg daily for 30 days, then increase to 4 mg.
Take tablets once daily on an empty stomach with water.
Wait at least 30 minutes after taking before eating or drinking.
Always follow your doctor's specific instructions for your dose.
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Side effects

Common

nauseaabdominal paindiarrheadecreased appetitevomitingconstipationthyroid tumors

Serious

acute pancreatitisdiabetic retinopathy complicationssevere gastrointestinal reactions
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Warnings

⚠ Important warnings

  • Risk of thyroid C-cell tumors; contraindicated in patients with a history of medullary thyroid carcinoma.
  • Increased risk of hypoglycemia when used with insulin or insulin secretagogues.
  • Monitor for acute pancreatitis and severe gastrointestinal reactions.
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Drug interactions

  • Insulin secretagoguesincreased risk of hypoglycemiaMonitor
  • Levothyroxineincreased exposure when taken together.Caution

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).