MedDataToolPantoprazole sodium is a medication used to treat conditions like erosive esophagitis caused by gastroesophageal reflux disease (GERD) and certain long-term stomach acid conditions. It works by reducing the amount of acid your stomach produces, helping to heal the esophagus and relieve symptoms like heartburn. You typically take it as a delayed-release tablet, starting with a dose of 40 mg once daily for up to 8 weeks, and it can be taken with or without food. It's important to know that this medication should not be taken if you are allergic to it or any similar medications. Additionally, if you are taking clopidogrel, a blood thinner, be aware that pantoprazole may reduce its effectiveness.
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Uses
- Short-term treatment of erosive esophagitis associated with GERD.
- Maintenance of healing of erosive esophagitis.
- Long-term treatment of pathological hypersecretory conditions including Zollinger-Ellison Syndrome.
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Dosage
Adults: 40 mg once daily for up to 8 weeks for erosive esophagitis.
Children (5 years and older): 20 mg or 40 mg once daily for up to 8 weeks.
Adults: 40 mg once daily for maintenance of healing.
Adults: 40 mg twice daily for Zollinger-Ellison Syndrome.
Swallow tablets whole, with or without food.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
headachediarrheanauseaabdominal painvomitingdizzinessacute tubulointerstitial nephritis
Serious
Clostridium difficile-associated diarrheabone fracturesevere skin reactionsvitamin B-12 deficiencyhypomagnesemia
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Warnings
⚠ Important warnings
- Safety of treatment beyond 8 weeks in children not established.
- Monitor for Clostridium difficile-associated diarrhea.
- Risk of bone fractures.
- May cause severe skin reactions.
- Possible vitamin B-12 deficiency with long-term use.
- Hypomagnesemia may occur.
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Drug interactions
- Warfarinincreased bleeding riskCaution
- Clopidogrelno significant effect on exposureCaution
- Methotrexatemay increase toxicityCaution
- Mycophenolate mofetilreduced effectivenessCaution
- Antiretroviralsvariable effects on drug levelsCaution
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Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).