MedDataToolParoxetine is a medication used to treat various conditions, including depression, anxiety disorders, and post-traumatic stress disorder. It works by increasing the levels of serotonin, a chemical in the brain that helps improve mood. You take it as a tablet once a day, usually starting with a dose of 20 mg, which can be increased up to a maximum of 60 mg depending on your needs. It's important to know that you should not take paroxetine if you are currently using monoamine oxidase inhibitors (MAOIs) or have taken them within the last 14 days, as this can lead to serious side effects. Additionally, if you are elderly or have severe kidney or liver problems, your starting dose should be lower, at 10 mg per day.
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Uses
- Major depressive disorder (MDD).
- Obsessive compulsive disorder (OCD).
- Panic disorder (PD).
- Social anxiety disorder (SAD).
- Generalized anxiety disorder (GAD).
- Posttraumatic stress disorder (PTSD).
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Dosage
Starting dose for MDD, OCD, PD, PTSD is 20 mg daily.
Maximum dose for MDD is 50 mg, for OCD is 60 mg, for PD is 60 mg, for PTSD is 50 mg.
Starting dose for SAD and GAD is 20 mg daily.
Elderly or patients with severe kidney or liver issues start at 10 mg daily, max 40 mg.
Take once daily in the morning, with or without food.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
nauseadizzinessdry mouthinsomniasweatingdecreased appetite
Serious
suicidal thoughtsserotonin syndromeincreased risk of bleedingseizures
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Warnings
⚠ Important warnings
- Increased risk of suicidal thoughts in young adults.
- Not approved for use in pediatric patients.
- Screen for bipolar disorder before starting treatment.
- Avoid use with MAOIs to prevent serotonin syndrome.
- Monitor for bleeding if taking with anticoagulants.
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Drug interactions
- MAOIsrisk of serotonin syndromeCaution
- Pimozideincreased risk of heart issuesMonitor
- Thioridazineincreased risk of heart issuesMonitor
- Warfarinincreased risk of bleedingMonitor
- Tamoxifenreduced effectiveness.Caution
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Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).