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Questran

Generic: Cholestyramine

Rx only
Bile Acid Sequestrant✓ FDA-verified
View full FDA label ↗
Questran is a medication used to help lower high cholesterol levels and relieve itching caused by certain liver problems. It works by binding to bile acids in the intestines, which helps to remove cholesterol from the body. You take it as a powder mixed with water or another drink, starting with one packet or scoop once or twice a day, and you can increase the dose up to six packets a day if needed. It's important to know that Questran should not be used if you have a complete blockage of the bile ducts. Additionally, it may work better when taken along with certain cholesterol-lowering medications like statins.

Uses

  • High cholesterol.
  • Pruritus from partial biliary obstruction.

Dosage

Start with 1 packet or scoop once or twice a day.
Maintenance is 2 to 4 packets daily, divided into two doses.
Maximum dose is 6 packets daily.
Take with meals, but avoid dry form.
Always follow your doctor's specific instructions for your dose.

Side effects

Common

constipationLess common: abdominal painflatulencenauseavomitingintestinal obstruction

Serious

bleeding tendenciesvitamin deficiencies
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Warnings

⚠ Important warnings

  • Contains phenylalanine in QUESTRAN LIGHT.
  • May interfere with absorption of other medications.
  • Not for patients with certain secondary causes of high cholesterol.

Drug interactions

  • Warfarinmay delay absorptionCaution
  • Thiazide diureticsmay delay absorptionCaution
  • Tetracyclinemay delay absorptionCaution
  • Digitalismay interfere with absorptionCaution
  • Fat-soluble vitaminsmay prevent absorption.Caution

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Answers pulled from the FDA label only.

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).