MedDataToolRiomet is a medication used to help control blood sugar levels in adults and children aged 10 and older who have type 2 diabetes, especially when combined with a healthy diet and exercise. It works by improving how your body handles sugar, reducing the amount of sugar produced by the liver, and helping your body use insulin better. You typically take it by mouth, starting with 500 mg twice a day or 850 mg once a day, and the dose can be increased weekly up to a maximum of 2,550 mg per day. It's important to know that Riomet should not be used if you have severe kidney problems, as it can worsen kidney function. Additionally, if you're taking other medications that affect kidney function, like certain diuretics, you should discuss this with your doctor, as they may impact how well Riomet works.
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Uses
- Type 2 diabetes mellitus in adults.
- Type 2 diabetes mellitus in pediatric patients 10 years and older.
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Dosage
Adults: Start with 500 mg (5 mL) twice a day or 850 mg (8.5 mL) once a day with meals.
Increase by 500 mg (5 mL) weekly or 850 mg (8.5 mL) every 2 weeks, up to 2,550 mg (25.5 mL) per day.
Pediatric patients: Start with 500 mg (5 mL) twice a day with meals, up to 2,000 mg (20 mL) per day.
Monitor renal function before starting and during treatment.
Discontinue if renal function worsens significantly.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
DiarrheanauseavomitingflatulenceheadacheLactic acidosis
Serious
vitamin B12 deficiencyhypoglycemia
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Warnings
⚠ Important warnings
- Risk of lactic acidosis, especially in patients with renal impairment.
- Do not use if eGFR is below 30 mL/min.
- Not recommended for eGFR between 30 to 45 mL/min.
- Discontinue if eGFR falls below 30 mL/min.
- Caution with iodinated contrast imaging procedures.
- Excessive alcohol intake may increase risk.
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Drug interactions
- Topiramatemay increase risk of lactic acidosisCaution
- Cimetidinemay increase metformin levelsCaution
- Ranolazinemay increase metformin levelsCaution
- Dolutegravirmay increase metformin levelsCaution
- Alcoholcan enhance metformin's effects on lactate.Caution
Ask about this drug
Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).